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Cellosaurus SAL2 (CVCL_F122)

[Text version]
Cell line name SAL2
Synonyms SAL-2
Accession CVCL_F122
Resource Identification Initiative To cite this cell line use: SAL2 (RRID:CVCL_F122)
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S862 ! SAL1
CVCL_9681 ! STA-ET-1
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=8378080
Kovar H., Auinger A., Jug G., Aryee D.N.T., Zoubek A., Salzer-Kuntschik M., Gadner H.
Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.
Oncogene 8:2683-2690(1993)

PubMed=9393981; DOI=10.1038/sj.onc.1201397
Kovar H., Jug G., Aryee D.N.T., Zoubek A., Ambros P.F., Gruber B., Windhager R., Gadner H.
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Oncogene 15:2225-2232(1997)

PubMed=15192123; DOI=10.1158/1541-7786.296.2.5
Pospisilova S., Siligan C., Ban J., Jug G., Kovar H.
Constitutive and DNA damage inducible activation of pig3 and MDM2 genes by tumor-derived p53 mutant C277Y.
Mol. Cancer Res. 2:296-304(2004)

Cross-references
Encyclopedic resources Wikidata; Q54952084
Polymorphism and mutation databases IARC_TP53; 23640
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number12