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Cellosaurus SAL2 (CVCL_F122)

[Text version]
Cell line name SAL2
Synonyms SAL-2
Accession CVCL_F122
Resource Identification Initiative To cite this cell line use: SAL2 (RRID:CVCL_F122)
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_S862 ! SAL1
CVCL_9681 ! STA-ET-1
Sex of cell Female
Age at sampling 13Y
Category Cancer cell line
Publications

PubMed=8378080
Heinrich Kovar, Andreas Auinger, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Mechthild Salzer-Kuntschik, Helmut Gadner;
Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.
Oncogene 8:2683-2690(1993)

PubMed=9393981; DOI=10.1038/sj.onc.1201397
Heinrich Kovar, Gunhild Jug, Dave N.T. Aryee, Andreas Zoubek, Peter F. Ambros, Bernadette Gruber, Reinhard Windhager, Helmut Gadner;
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors.
Oncogene 15:2225-2232(1997)

PubMed=15192123; DOI=10.1158/1541-7786.296.2.5
Sarka Pospisilova, Christine Siligan, Jozet Ban, Gunhild Jug, Heinrich Kovar;
Constitutive and DNA damage inducible activation of pig3 and MDM2 genes by tumor-derived p53 mutant C277Y.
Mol. Cancer Res. 2:296-304(2004)

Cross-references
Encyclopedic resources Wikidata; Q54952084
Polymorphism and mutation databases IARC_TP53; 23640
Entry history
Entry creation22-Oct-2012
Last entry update21-Mar-2023
Version number12