| Cell line name |
BT-20N |
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| Accession |
CVCL_F0XP |
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| Resource Identification Initiative |
To cite this cell line use: BT-20N (RRID:CVCL_F0XP) |
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| Comments |
Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1759; CDH2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Breast; UBERON=UBERON_0000310. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro539Arg (c.1616C>G); ClinVar=VCV000376243; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ile388Ser (c.1163T>G); ClinVar=VCV000665312; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:9884; RB1; Simple; p.Pro515Leu (c.1544C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys132Gln (c.394A>C); ClinVar=VCV000376628; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Invasive breast carcinoma of no special type (NCIt: C4194) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0178 (BT-20) |
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| Sex of cell |
Female |
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| Age at sampling |
74Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=10545506; DOI=10.1083/jcb.147.3.631; PMCID=PMC2151177
Marvin T. Nieman, Ryan Sanford Prudoff, Keith R. Johnson, Margaret Jean Wheelock;
N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression.
J. Cell Biol. 147:631-644(1999) |
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| Entry history |
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| Entry creation | 27-Nov-2025 |
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| Last entry update | 27-Nov-2025 |
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| Version number | 1 |
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