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Cellosaurus iPSC Dup15q_iso (CVCL_F0TY)

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Cell line name iPSC Dup15q_iso
Synonyms clone 3-41
Accession CVCL_F0TY
Resource Identification Initiative To cite this cell line use: iPSC Dup15q_iso (RRID:CVCL_F0TY)
Comments Population: Caucasian.
Characteristics: Using CRISPR/Cas9 the extra isodicentric chromosone 15 was removed in a four step process (PubMed=39059105).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; RNAseq; Single cell.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Autism spectrum disorder (NCIt: C88412)
Chromosome 15q11-q13 duplication syndrome (NCIt: C126692)
15q11q13 microduplication syndrome (ORDO: Orphanet_238446)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F0TX (iPSC Dup15q)
Sex of cell Female
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=39059105; DOI=10.1016/j.ejcb.2024.151446
Haruka Munezane, Keiko Imamura, Naoko Fujimoto, Akitsu Hotta, Hiroshi Yukitake, Haruhisa Inoue;
Elimination of the extra chromosome of Dup15q syndrome iPSCs for cellular and molecular investigation.
Eur. J. Cell Biol. 103:151446.1-151446.11(2024)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1