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Cellosaurus SH-EP1-pCEP4-ha7 (CVCL_F0SS)

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Cell line name SH-EP1-pCEP4-ha7
Synonyms SH-EP1-pCEP4-halpha7
Accession CVCL_F0SS
Resource Identification Initiative To cite this cell line use: SH-EP1-pCEP4-ha7 (RRID:CVCL_F0SS)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1960; CHRNA7.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0F47 (SH-EP1)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=15590768; DOI=10.1124/jpet.104.079004
Jian-Hong Peng, John D. Fryer, Raymond S. Hurst, Katherine Marie Schroeder, Andrew A. George, Steven Morrissy, Vincent E. Groppi, Sherry S. Leonard, Ronald John Lukas;
High-affinity epibatidine binding of functional, human alpha7-nicotinic acetylcholine receptors stably and heterologously expressed de novo in human SH-EP1 cells.
J. Pharmacol. Exp. Ther. 313:24-35(2005)

Entry history
Entry creation27-Nov-2025
Last entry update27-Nov-2025
Version number1