Cellosaurus cell line PC-3 cFER S-A2 (CVCL

Entry history
Cell line name	PC-3 cFER S-A2
Synonyms	S-A2
Accession	CVCL_F0RZ
Resource Identification Initiative	To cite this cell line use: PC-3 cFER S-A2 (RRID:CVCL_F0RZ)
Comments	Population: Caucasian. Doubling time: 31 +- 2 hours (PubMed=10687853). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=VGNC; VGNC:40818; Dog FER (Note=420 bp fragment of coding region in sense orientation). Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (PubMed=8510267).
Disease	Prostate carcinoma (NCIt: C4863)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0035 (PC-3)
Sex of cell	Male
Age at sampling	62Y
Category	Cancer cell line
Publications	PubMed=10687853; DOI=10.1016/s0303-7207(99)00205-1 Pierre Allard, Amina Zoubeidi, Linh T. Nguyen, Sylvain Tessier, Simon Tanguay, Mario Chevrette, Armen Garo Aprikian, Simone Chevalier; Links between Fer tyrosine kinase expression levels and prostate cell proliferation. Mol. Cell. Endocrinol. 159:63-77(2000)
Entry creation	27-Nov-2025
Last entry update	27-Nov-2025
Version number	1