Cellosaurus logo
expasy logo

Cellosaurus HEK293-ARV7-PSA-E/P-LUC (CVCL_F0L6)

[Text version]
Cell line name HEK293-ARV7-PSA-E/P-LUC
Accession CVCL_F0L6
Resource Identification Initiative To cite this cell line use: HEK293-ARV7-PSA-E/P-LUC (RRID:CVCL_F0L6)
Comments Characteristics: Transfected with both a pcDNA3.1-AR-V7 plasmid and a PSA/e P-LUC plasmid where theluciferase gene expression is driven by the PSA promoter and enhancer (PubMed=24740322).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:644; AR (Note=Isoform ARv7).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=24740322; DOI=10.1158/1078-0432.CCR-13-3296; PMCID=PMC4058390
Cheng-Fei Liu, Wei Lou, Ye-Zi Zhu, Nagalakshmi Nadiminty, Chad T. Schwartz, Christopher P. Evans, Allen C. Gao;
Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer.
Clin. Cancer Res. 20:3198-3210(2014)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1