Cellosaurus cell line HMOCC-1 (CVCL

Cellosaurus HMOCC-1 (CVCL_F0KX)

Entry history
Cell line name	HMOCC-1
Synonyms	Human Monoclonal antibody for Ovarian Clear cell Carcinoma-1
Accession	CVCL_F0KX
Resource Identification Initiative	To cite this cell line use: HMOCC-1 (RRID:CVCL_F0KX)
Comments	Monoclonal antibody isotype: IgM. Monoclonal antibody target: Disulfated oligosaccharide SO(3)->3Gal(beta1)->4GlcNAc(beta1)-3(+-SO(3)->6)Gal(beta1)-4GlcNAc(beta1). Miscellaneous: As the immunized splenic B-cells are from KM mice the produced mAB is of human origin.
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy	Parent: CVCL_2199 (Sp2/0-Ag14)
Category	Hybridoma
Publications	PubMed=15491748; DOI=10.1016/j.ygyno.2004.06.024 Nao Suzuki, Daisuke Aoki, Yutaka Tamada, Nobuyuki Susumu, Kimiko Orikawa, Katsumi Tsukazaki, Motoko Sakayori, Atsushi Suzuki, Takeshi Fukuchi, Makio Mukai, Kyoko Kojima-Aikawa ...Show all 13 authors... , Isao Ishida, Shiro Nozawa; Show fewer authors HMOCC-1, a human monoclonal antibody that inhibits adhesion of ovarian cancer cells to human mesothelial cells. Gynecol. Oncol. 95:290-298(2004) PubMed=22194598; DOI=10.1074/jbc.M111.305334; PMCID=PMC3307324 Toshiaki K. Shibata, Fumiko Matsumura, Ping Wang, Shin-Yi Yu, Chi-Chi Chou, Kay-Hooi Khoo, Kazuko Kitayama, Tomoya O. Akama, Kazuhiro Sugihara, Naohiro Kanayama, Kyoko Kojima-Aikawa ...Show all 16 authors... , Peter H. Seeberger, Minoru Fukuda, Atsushi Suzuki, Daisuke Aoki, Michiko N. Fukuda; Show fewer authors Identification of mono- and disulfated N-acetyl-lactosaminyl Oligosaccharide structures as epitopes specifically recognized by humanized monoclonal antibody HMOCC-1 raised against ovarian cancer. J. Biol. Chem. 287:6592-6602(2012)
Entry creation	14-Aug-2025
Last entry update	14-Aug-2025
Version number	1