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Cellosaurus JXQ-3D-783R1 (CVCL_F0K0)

[Text version]
Cell line name JXQ-3D-783R1
Accession CVCL_F0K0
Resource Identification Initiative To cite this cell line use: JXQ-3D-783R1 (RRID:CVCL_F0K0)
Comments Population: Chinese.
Characteristics: Tumorigenic when transplanted subcutaneously into nude mice (PubMed=38113975).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Lys1593Serfs*57 (c.4778del); ClinVar=VCV000486786; Zygosity=Unspecified (PubMed=38113975).
  • Mutation; HGNC; HGNC:6193; JAK3; Simple; p.Arg403His (c.1208G>A); ClinVar=VCV000803543; Zygosity=Unspecified (PubMed=38113975).
  • Mutation; HGNC; HGNC:13726; KMT2C; Simple; p.Pro3380Thr (c.10138C>A); Zygosity=Unspecified (PubMed=38113975).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser269Alafs*82 (c.805del); Zygosity=Unspecified (PubMed=38113975).
Disease Hilar cholangiocarcinoma (NCIt: C36077)
Klatskin tumor (ORDO: Orphanet_99978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_F0K1 ! JXQ-3D-783R2
CVCL_F0K2 ! JXQ-3D-783R3
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): PubMed=38113975

Markers:
AmelogeninX
CSF1PO11
D2S133823,24
D3S135815,17
D5S81811,12
D6S104315
D7S82010,11
D8S117913
D12S39115
D13S31711
D16S5399
D18S5117
D19S43313,14.2
D21S1128,30
FGA20,22.2
Penta D9
Penta E11,16
TH017,8
TPOX8
vWA14

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Publications

PubMed=38113975; DOI=10.1016/j.ygeno.2023.110765
Fei-Ling Feng, Xiang-Lei Xing, Guo-Juan Jiang, Xiao-Ya Xu, Bin Li, Zhi-Zhen Li, Zheng-Hua Xie, Yue Wu, Xiao-Fang Li, Qing-Xiang Gao, Dong-Yu Liu ...Show all 16 authors... , Yang Shen, Jian-Yang Ao, Da-Dong Zhang, Yan-Xin Chang, Xiao-Qing Jiang; Show fewer authors
Genomic and transcriptomic characteristics of 12 novel primary cell lines derived from three patients with cholangiocarcinoma.
Genomics 116:110765-110765(2024)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1