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Cellosaurus HeLa rCD4 m2 (CVCL_F0JL)

[Text version]
Cell line name HeLa rCD4 m2
Synonyms HeLa m2
Accession CVCL_F0JL
Resource Identification Initiative To cite this cell line use: HeLa rCD4 m2 (RRID:CVCL_F0JL)
Comments Population: African American.
Genetic integration: Method=Transfection; Gene=RGD; 2306; Cd4 (Note=With p.Gly36-Thr62 replaced by equivalent region of human CD4).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=8459222; DOI=10.1084/jem.177.4.949; PMCID=PMC2190986
James H.M. Simon, Chamorro Somoza, Gerard Alphonse Schockmel, Matthew Collin, Simon J. Davis, Alan Frederick Williams, Williams S. James;
A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.
J. Exp. Med. 177:949-954(1993)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1