Cellosaurus HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP (CVCL_F0F7)
| Cell line name | HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP |
|---|---|
| Synonyms | Syn10 TauRD-YFP |
| Accession | CVCL_F0F7 |
| Resource Identification Initiative | To cite this cell line use: HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP (RRID:CVCL_F0F7) |
| Comments | Characteristics: Transduced with an all-in-one Tet-Off construct for the controllable expression of untagged SNCA p.Ala53Thr (from parent cell line). Characteristics: Transfected with a plasmid encoding a EYFP-tagged Tau repeat domain, bearing FTD mutations (Direct_author_submission). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11138; SNCA (Note=With p.Ala53Thr). Genetic integration: Method=Transduction; Gene=UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd). Genetic integration: Method=Transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transfection; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6893; MAPT (Note=With p.Pro301Leu and p.Val337Met). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Miscellaneous: Cell line information from personal communication of Sitron, Cole S. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_D4BW (HEK293T TetOff-SNCA-A53T) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Entry history | |
| Entry creation | 14-Aug-2025 |
| Last entry update | 31-Mar-2026 |
| Version number | 3 |