Cellosaurus HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP (CVCL_F0F7)
Cell line name | HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP |
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Synonyms | Syn10 TauRD-YFP |
Accession | CVCL_F0F7 |
Resource Identification Initiative | To cite this cell line use: HEK293T TetOff-SNCA-A53T TauRD (P301L/V337M)-EYFP (RRID:CVCL_F0F7) |
Comments | Characteristics: Transduced with an all-in-one Tet-Off construct for the controllable expression of untagged SNCA p.Ala53Thr (from parent cell line). Characteristics: Transfected with a plasmid encoding a EYFP-tagged Tau repeat domain, bearing FTD mutations (Direct_author_submission). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11138; SNCA (Note=With p.Ala53Thr). Genetic integration: Method=Transduction; Gene=UniProtKB; P0C2P0; Aspergillus terreus blasticidin-S deaminase (Bsd). Genetic integration: Method=Transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transduction; Gene=UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (Note=With p.Met1_Arg360del). Genetic integration: Method=Transfection; Gene=FPbase; 8DNLG; EYFP (Note=Enhanced YFP). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6893; MAPT (Note=With p.Pro301Leu and p.Val337Met). Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA). Miscellaneous: Cell line information from personal communication of Sitron, Cole S. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_D4BW (HEK293T TetOff-SNCA-A53T) |
Sex of cell | Female |
Age at sampling | Fetus |
Category | Transformed cell line |
Entry history | |
Entry creation | 14-Aug-2025 |
Last entry update | 14-Aug-2025 |
Version number | 1 |