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Cellosaurus CHO-K1 DrToyR-18 (CVCL_F0EB)

[Text version]
Cell line name CHO-K1 DrToyR-18
Synonyms DrToyR-18
Accession CVCL_F0EB
Resource Identification Initiative To cite this cell line use: CHO-K1 DrToyR-18 (RRID:CVCL_F0EB)
Comments Characteristics: Auxotrophic for glycine (from parent cell line).
Selected for resistance to: ChEBI; CHEBI_38001; 2,6-diaminopurine (2,6-DAP).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Selected for resistance to: ChEBI; CHEBI_134606; Toyocamycin (Vengicide).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; P55262; Adk; Simple; p.Glu242Lys (c.724G>A); Zygosity=Unspecified (PubMed=21586167).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_F0E6 (CHO-K1 DR31)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=21586167; DOI=10.1186/1471-2091-12-22; PMCID=PMC3118340
Xian-Ying Amy Cui, Tanvi Agarwal, Bhag Singh, Radhey S. Gupta;
Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics.
BMC Biochem. 12:22.1-22.14(2011)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1