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Cellosaurus CHO FomR-4 (CVCL_F0DJ)

[Text version]
Cell line name CHO FomR-4
Synonyms FomR-4; FomR4
Accession CVCL_F0DJ
Resource Identification Initiative To cite this cell line use: CHO FomR-4 (RRID:CVCL_F0DJ)
Comments Selected for resistance to: ChEBI; CHEBI_42452; Formycin A.
Selected for resistance to: ChEBI; CHEBI_42654; Formycin B.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; P55262; Adk; Simple; p.Ser191Phe; Zygosity=Unspecified (PubMed=21586167).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=6312294; DOI=10.1128/mcb.3.8.1468-1477.1983; PMCID=PMC369993
Kamal Deep Mehta, Radhey S. Gupta;
Formycin B-resistant mutants of Chinese hamster ovary cells: novel genetic and biochemical phenotype affecting adenosine kinase.
Mol. Cell. Biol. 3:1468-1477(1983)

PubMed=4075228; DOI=10.1139/o85-129
Kamal Deep Mehta, Radhey S. Gupta;
Chinese hamster ovary cell mutants specifically affected in the phosphorylation of C-purine nucleosides.
Can. J. Biochem. Cell Biol. 63:1044-1048(1985)

PubMed=3003929; DOI=10.1007/BF01560724
Kamal Deep Mehta, Radhey S. Gupta;
Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts.
Somat. Cell Mol. Genet. 12:21-31(1986)

PubMed=3020927; DOI=10.1007/978-1-4684-1248-2_93
Radhey S. Gupta, Kamal Deep Mehta;
Genetic and biochemical characteristics of three different types of mutants of mammalian cells affected in adenosine kinase.
Adv. Exp. Med. Biol. 195:595-603(1986)

PubMed=8917457; DOI=10.1111/j.1432-1033.1995.tb20220.x_1
Bhag Singh, Wei-Hua Hao, Zai-Chuan Wu, Bernhard J. Eigl, Radhey S. Gupta;
Cloning and characterization of cDNA for adenosine kinase from mammalian (Chinese hamster, mouse, human and rat) species. High frequency mutants of Chinese hamster ovary cells involve structural alterations in the gene.
Eur. J. Biochem. 241:564-571(1996)

PubMed=21586167; DOI=10.1186/1471-2091-12-22; PMCID=PMC3118340
Xian-Ying Amy Cui, Tanvi Agarwal, Bhag Singh, Radhey S. Gupta;
Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics.
BMC Biochem. 12:22.1-22.14(2011)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1