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Cellosaurus CHO Toyr-4 (CVCL_F0DC)

[Text version]
Cell line name CHO Toyr-4
Synonyms Toyr-4; Toyr4
Accession CVCL_F0DC
Resource Identification Initiative To cite this cell line use: CHO Toyr-4 (RRID:CVCL_F0DC)
Comments Selected for resistance to: ChEBI; CHEBI_134606; Toyocamycin (Vengicide).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=217113; DOI=10.1007/BF01543160
Radhey S. Gupta, Louis Siminovitch;
Genetic and biochemical studies with the adenosine analogs toyocamycin and tubercidin: mutation at the adenosine kinase locus in Chinese hamster cells.
Somatic Cell Genet. 4:715-735(1978)

PubMed=6178748; DOI=10.1002/jcp.1041110310
Radhey S. Gupta, Malcolm Raymond K. Moffat;
Synergistic effect of purine derivatives on the toxicity of pyrazofurin and 6-azauridine towards cultured mammalian cells.
J. Cell. Physiol. 111:291-294(1982)

PubMed=6312294; DOI=10.1128/mcb.3.8.1468-1477.1983; PMCID=PMC369993
Kamal Deep Mehta, Radhey S. Gupta;
Formycin B-resistant mutants of Chinese hamster ovary cells: novel genetic and biochemical phenotype affecting adenosine kinase.
Mol. Cell. Biol. 3:1468-1477(1983)

PubMed=4075228; DOI=10.1139/o85-129
Kamal Deep Mehta, Radhey S. Gupta;
Chinese hamster ovary cell mutants specifically affected in the phosphorylation of C-purine nucleosides.
Can. J. Biochem. Cell Biol. 63:1044-1048(1985)

PubMed=3003929; DOI=10.1007/BF01560724
Kamal Deep Mehta, Radhey S. Gupta;
Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts.
Somat. Cell Mol. Genet. 12:21-31(1986)

PubMed=3020927; DOI=10.1007/978-1-4684-1248-2_93
Radhey S. Gupta, Kamal Deep Mehta;
Genetic and biochemical characteristics of three different types of mutants of mammalian cells affected in adenosine kinase.
Adv. Exp. Med. Biol. 195:595-603(1986)

PubMed=21586167; DOI=10.1186/1471-2091-12-22; PMCID=PMC3118340
Xian-Ying Amy Cui, Tanvi Agarwal, Bhag Singh, Radhey S. Gupta;
Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics.
BMC Biochem. 12:22.1-22.14(2011)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1