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Cellosaurus NP361-LMP1/hTERT (CVCL_F0CG)

[Text version]
Cell line name NP361-LMP1/hTERT
Synonyms NP361LMP1/hTERT
Accession CVCL_F0CG
Resource Identification Initiative To cite this cell line use: NP361-LMP1/hTERT (RRID:CVCL_F0CG)
Comments Population: Chinese.
Senescence: Senesces at ~40 PDL (PubMed=20827769).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; R4R994; Epstein-Barr virus (strain 2117) latent membrane protein 1 (LMP1).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Donor information: Established from the non-malignant tissue of a patient diagnosed with undifferentiated nasopharyngeal carcinoma (from parent cell line).
Derived from site: In situ; Pharynx, nasopharynx; UBERON=UBERON_0001728.
Cell type: Epithelial cell of nasopharynx; CL=CL_1001573.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_F0CF (NP361-LMP1)
Sex of cell Female
Age at sampling 50Y
Category Finite cell line
Publications

PubMed=20827769; DOI=10.1002/jmv.21875
Yim-Ling Yip, Chi-Man Tsang, Wen Deng, Pak-Yan Cheung, Yue-Sheng Jin, Annie Lai-Man Cheung, Maria Li Lung, George Sai-Wah Tsao;
Expression of Epstein-Barr virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells.
J. Med. Virol. 82:1711-1723(2010)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1