Cellosaurus cell line NP446 (CVCL

Cellosaurus NP446 (CVCL_F0CB)

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Cell line name

NP446

Accession

CVCL_F0CB

Resource Identification Initiative

To cite this cell line use: NP446 (RRID:CVCL_F0CB)

Comments

Population: Chinese.
Senescence: Senesces at 10 PDL (PubMed=20827769; PubMed=24167620).
Derived from site: In situ; Pharynx, nasopharynx, epithelium; UBERON=UBERON_0001951.
Cell type: Epithelial cell of nasopharynx; CL=CL_1001573.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_F0CH (NP446-Bmi-1)

CVCL_F0CI (NP446-hTERT)

CVCL_F0CJ (NP446-LMP1)

Sex of cell

Female

Age at sampling

42Y

Category

Finite cell line

Publications

PubMed=20827769; DOI=10.1002/jmv.21875
Yim-Ling Yip, Chi-Man Tsang, Wen Deng, Pak-Yan Cheung, Yue-Sheng Jin, Annie Lai-Man Cheung, Maria Li Lung, George Sai-Wah Tsao;
Expression of Epstein-Barr virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells.
J. Med. Virol. 82:1711-1723(2010)

PubMed=24167620; DOI=10.1371/journal.pone.0078395; PMCID=PMC3805559
Yim-Ling Yip, Pei-Shin Pang, Wen Deng, Chi-Man Tsang, Mu-Sheng Zeng, Pok-Man Hau, Cornelia Man, Yue-Sheng Jin, Anthony Po-Wing Yuen, George Sai-Wah Tsao;
Efficient immortalization of primary nasopharyngeal epithelial cells for EBV infection study.
PLoS ONE 8:e78395.1-e78395.13(2013)

Entry history

Entry creation

14-Aug-2025

Last entry update

14-Aug-2025

Version number