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Cellosaurus FOSE2 (CVCL_F0B8)

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Cell line name FOSE2
Accession CVCL_F0B8
Resource Identification Initiative To cite this cell line use: FOSE2 (RRID:CVCL_F0B8)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2).
Derived from site: In situ; Ovary, surface epithelium; UBERON=UBERON_0001304.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Unspecified (from inference of genetic background of transgenic mouse used).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: KrasG12D/wtPtenloxP/loxPCD95loxP/loxPAmhr2-Cre transgenic.
Sex of cell Female
Category Spontaneously immortalized cell line
Publications

PubMed=29440125; DOI=10.15252/embr.201745336; PMCID=PMC5836092
Andrea E. Murmann, Quan Q. Gao, William E. Putzbach, Monal Patel, Elizabeth Thomas Bartom, Calvin Y. Law, Bryan B. Bridgeman, Si-Quan Chen, Kaylin M. McMahon, Colby Shad Thaxton, Marcus Ernst Peter;
Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells.
EMBO Rep. 19:e45336.1-e45336.15(2018)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1