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Cellosaurus 257-D (CVCL_F0AS)

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Cell line name 257-D
Synonyms 257-2D
Accession CVCL_F0AS
Resource Identification Initiative To cite this cell line use: 257-D (RRID:CVCL_F0AS)
Comments Monoclonal antibody isotype: IgG1, lambda.
Monoclonal antibody target: UniProtKB; P05877; HIV-1 isolate MN env (Note=Selected with the peptide 306-YNKRKRIHIGPGRAFYTTKNIIG-328 from gp120 V3 region. Also reacts with isolate ARV2/SF2).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3419 (SHM-D33)
Parent: CVCL_F0AF (257-2)
Category Hybridoma
Publications

PubMed=2014246; DOI=10.1073/pnas.88.8.3238; PMCID=PMC51421
Miroslaw K. Gorny, Jian-Yin Xu, Vasiliki Gianakakos, Sylwia Karwowska, Constance Williams, Haynes W. Sheppard, Carl Veith Hanson, Susan Zolla-Pazner;
Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein.
Proc. Natl. Acad. Sci. U.S.A. 88:3238-3242(1991)

PubMed=7678279
Miroslaw K. Gorny, Jian-Yin Xu, Sylwia Karwowska, Aby Buchbinder, Susan Zolla-Pazner;
Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120.
J. Immunol. 150:635-643(1993)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1