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Cellosaurus ATH16BE LCL (CVCL_F087)

[Text version]
Cell line name ATH16BE LCL
Synonyms ATH16Be LCL; Ataxia Telangiectasia Heterozygote 16 BEthesda LCL; GM03188; GM 3188; GM03188A
Accession CVCL_F087
Resource Identification Initiative To cite this cell line use: ATH16BE LCL (RRID:CVCL_F087)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 795; ATM; Simple; p.Lys2756Ter (c.8266A>T); ClinVar=VCV000135780; Zygosity=Heterozygous (Coriell=GM03188).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_F086 ! ATH16BE
Sex of cell Female
Age at sampling 36Y
Category Transformed cell line
Publications

PubMed=6173245; DOI=10.1016/0014-4827(82)90040-4
Kohn P.H., Kraemer K.H., Buchanan J.K.
Influence of ataxia telangiectasia gene dosage on bleomycin-induced chromosome breakage and inhibition of replication in human lymphoblastoid cell lines.
Exp. Cell Res. 137:387-395(1982)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=23943852; DOI=10.1152/physiolgenomics.00064.2013
Zhang L.-W., Simpson D.A., Innes C.L., Chou J., Bushel P.R., Paules R.S., Kaufmann W.K., Zhou T.
Gene expression signatures but not cell cycle checkpoint functions distinguish AT carriers from normal individuals.
Physiol. Genomics 45:907-916(2013)

Cross-references
Cell line collections (Providers) Coriell; GM03188
Cell line databases/resources CLO; CLO_0013413
Biological sample resources BioSample; SAMN00808281
Encyclopedic resources Wikidata; Q54837923
Gene expression databases GEO; GSM1116563
GEO; GSM1116564
GEO; GSM1116605
GEO; GSM1116606
GEO; GSM1116607
GEO; GSM1116608
Entry history
Entry creation22-Oct-2012
Last entry update30-Jan-2024
Version number19