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Cellosaurus HBEC7-KT (CVCL_ER02)

[Text version]
Cell line name HBEC7-KT
Synonyms HBEC7KT; HBEC7kt
Accession CVCL_ER02
Resource Identification Initiative To cite this cell line use: HBEC7-KT (RRID:CVCL_ER02)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88357; Cdk4.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Telomerase immortalized cell line
Publications

PubMed=30038707; DOI=10.18632/oncotarget.25642; PMCID=PMC6049873
Li-Qin Du, Zhen-Ze Zhao, Milind Bhalchandra Suraokar, Spencer S. Shelton, Xiu-Ye Ma, Tzu-Hung Hsiao, John D. Minna, Ignacio Ivan Wistuba, Alexander Pertsemlidis;
LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer.
Oncotarget 9:29601-29618(2018)

Cross-references
Encyclopedic resources Wikidata; Q54881420
Gene expression databases GEO; GSM794413
Entry history
Entry creation26-Sep-2016
Last entry update14-Aug-2025
Version number15