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Cellosaurus IMC-1 (CVCL_EQ57)

[Text version]
Cell line name IMC-1
Accession CVCL_EQ57
Resource Identification Initiative To cite this cell line use: IMC-1 (RRID:CVCL_EQ57)
Comments Characteristics: IL2 dependent.
Doubling time: 24-36 hours (PubMed=14687616).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Natural killer cell lymphoblastic leukemia/lymphoma (NCIt: C82217)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
Publications

PubMed=14687616; DOI=10.1016/j.leukres.2003.08.014
Wong K.-F.
A novel EBV-negative natural killer cell line.
Leuk. Res. 28:225-227(2004)

PubMed=14687623; DOI=10.1016/S0145-2126(03)00254-6
Chen I.-M., Whalen M., Bankhurst A.D., Sever C.E., Doshi R., Hardekopf D., Montgomery K.D., Willman C.L.
A new human natural killer leukemia cell line, IMC-1. A complex chromosomal rearrangement defined by spectral karyotyping: functional and cytogenetic characterization.
Leuk. Res. 28:275-284(2004)

PubMed=21052088; DOI=10.1038/leu.2010.255
Iqbal J., Weisenburger D.D., Chowdhury A., Tsai M.-Y., Srivastava G., Greiner T.C., Kucuk C., Deffenbacher K.E., Vose J.M., Smith L., Au W.Y., Nakamura S., Seto M., Delabie J., Berger F., Loong F., Ko Y.-H., Sng I., Liu X., Loughran T.P. Jr., Armitage J.O., Chan W.-C.
International Peripheral T-cell Lymphoma Project
Natural killer cell lymphoma shares strikingly similar molecular features with a group of non-hepatosplenic gammadelta T-cell lymphoma and is highly sensitive to a novel aurora kinase A inhibitor in vitro.
Leukemia 25:348-358(2011)

Cross-references
Encyclopedic resources Wikidata; Q54897515
Gene expression databases GEO; GSM471998
Polymorphism and mutation databases Cosmic; 2785202
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number8