Cellosaurus cell line iWS780-2.10 (CVCL

Cross-references
Cell line name	iWS780-2.10
Synonyms	WS iPSC from AG00780 (clone 2.10)
Accession	CVCL_EQ41
Resource Identification Initiative	To cite this cell line use: iWS780-2.10 (RRID:CVCL_EQ41)
Comments	Omics: Transcriptomics; Microarray. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:12791; WRN; Simple; p.Arg369Ter (c.1105C>T) (c.1336C>T); ClinVar=VCV000005449; Zygosity=Homozygous (PubMed=24749076).
Disease	Werner syndrome (NCIt: C3447) Werner syndrome (ORDO: Orphanet_902)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_U282 (AG00780)
Sex of cell	Male
Age at sampling	60Y
Category	Induced pluripotent stem cell
Publications	PubMed=24749076; DOI=10.1016/j.stemcr.2014.02.006; PMCID=PMC3986587 Hoi-Hung Cheung, Xiao-Zhuo Liu, Lucile Canterel-Thouennon, Lu Li, Catherine Edmonson, Owen Murray Rennert; Telomerase protects Werner syndrome lineage-specific stem cells from premature aging. Stem Cell Reports 2:534-546(2014)
Encyclopedic resources	Wikidata; Q54898391
Gene expression databases	GEO; GSM1184290 GEO; GSM1184291
Entry history
Entry creation	26-Sep-2016
Last entry update	10-Apr-2025
Version number	12