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Cellosaurus ER-Cal-27 (CVCL_EI26)

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Cell line name ER-Cal-27
Accession CVCL_EI26
Resource Identification Initiative To cite this cell line use: ER-Cal-27 (RRID:CVCL_EI26)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_114785; Erlotinib.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (from parent cell line).
Disease Tongue adenosquamous carcinoma (NCIt: C173807)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1107 (CAL-27)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=25888065; DOI=10.1016/j.molonc.2015.03.008; PMCID=PMC4523436
Aditya Stanam, Laurie Love-Homan, Tisha S. Joseph, Madelyn Espinosa-Cotton, Andrean L. Simons;
Upregulated interleukin-6 expression contributes to erlotinib resistance in head and neck squamous cell carcinoma.
Mol. Oncol. 9:1371-1383(2015)

Cross-references
Encyclopedic resources Wikidata; Q54832416
Gene expression databases GEO; GSM1519077
GEO; GSM1519078
GEO; GSM1519079
Entry history
Entry creation26-Sep-2016
Last entry update10-Apr-2025
Version number16