Cellosaurus cell line JVE774 (CVCL

Cellosaurus JVE774 (CVCL_EG32)

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Cell line name

JVE774

Synonyms

JVE-774

Accession

CVCL_EG32

Resource Identification Initiative

To cite this cell line use: JVE774 (RRID:CVCL_EG32)

Comments

Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: Genomics; DNA methylation analysis.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Rectum; UBERON=UBERON_0001052.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln22Lys (c.64C>A); ClinVar=VCV000376325; Zygosity=Unspecified (PubMed=26894854).

Disease

Rectal adenocarcinoma (NCIt: C9383)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

61Y

Category

Cancer cell line

STR profile

Source(s): PubMed=26894854

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D5S818	12
D7S820	8
D13S317	11,12
D16S539	9,12
D21S11	28,29
TH01	9.3
TPOX	8,9
vWA	17

Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731
Arnoud Boot, Jaap D.H. van Eendenburg, Stijn Crobach, Dina Ruano, Frank Speetjens, Jan Calame, Jan Oosting, Hans Morreau, Tom van Wezel;
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170
Arnoud Boot, Jan Oosting, Jaap D.H. van Eendenburg, Peter J.K. Kuppen, Hans Morreau, Tom van Wezel;
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:e0184900.1-e0184900.16(2017)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_EG32

Encyclopedic resources

Wikidata; Q54899188

Gene expression databases

GEO; GSM1655614
GEO; GSM1655636

Entry history

Entry creation

13-Jul-2016

Last entry update

10-Apr-2025

Version number