Cellosaurus cell line JVE207 (CVCL

Cellosaurus JVE207 (CVCL_EG25)

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Cell line name

JVE207

Synonyms

JVE-207

Accession

CVCL_EG25

Resource Identification Initiative

To cite this cell line use: JVE207 (RRID:CVCL_EG25)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~30-50 hours (DSMZ=ACC-820).
Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: Genomics; DNA methylation analysis.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Colon, descending; UBERON=UBERON_0001158.

Sequence variations

Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=26894854).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26894854).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

67Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-820; PubMed=26894854

Markers:

Amelogenin	X
CSF1PO	10
D2S1338	17,21
D3S1358	16,17
D5S818	12
D7S820	9,12
D8S1179	12
D13S317	12,13
D16S539	11
D18S51	16
D19S433	13,15
D21S11	28
FGA	22
Penta D	12,13
Penta E	13,14
TH01	7,9
TPOX	8,9
vWA	15,17

Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731
Arnoud Boot, Jaap D.H. van Eendenburg, Stijn Crobach, Dina Ruano, Frank Speetjens, Jan Calame, Jan Oosting, Hans Morreau, Tom van Wezel;
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170
Arnoud Boot, Jan Oosting, Jaap D.H. van Eendenburg, Peter J.K. Kuppen, Hans Morreau, Tom van Wezel;
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:e0184900.1-e0184900.16(2017)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-820

Cell line databases/resources

cancercelllines; CVCL_EG25
DepMap; ACH-002662
DSMZCellDive; ACC-820

Encyclopedic resources

Wikidata; Q54899181

Gene expression databases

GEO; GSM1655607
GEO; GSM1655629

Entry history

Entry creation

13-Jul-2016

Last entry update

10-Apr-2025

Version number