Cellosaurus cell line JVE127 (CVCL

Cellosaurus JVE127 (CVCL_EG22)

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Cell line name

JVE127

Synonyms

JVE-127

Accession

CVCL_EG22

Resource Identification Initiative

To cite this cell line use: JVE127 (RRID:CVCL_EG22)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~2-3 days (DSMZ=ACC-813).
Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: Genomics; DNA methylation analysis.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Colon, ascending; UBERON=UBERON_0001156.

Sequence variations

Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=26894854).
Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=26894854).

Disease

Colon mucinous adenocarcinoma (NCIt: C7966)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

60Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-813; PubMed=26894854

Markers:

Amelogenin	X,Y
CSF1PO	11
D2S1338	18,19
D3S1358	16,18
D5S818	13
D7S820	8,12
D8S1179	15
D13S317	8,13
D16S539	12,13
D18S51	17
D19S433	13,14
D21S11	30
FGA	24
Penta D	10
Penta E	4,16
TH01	7
TPOX	11
vWA	16,18

Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731
Arnoud Boot, Jaap D.H. van Eendenburg, Stijn Crobach, Dina Ruano, Frank Speetjens, Jan Calame, Jan Oosting, Hans Morreau, Tom van Wezel;
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170
Arnoud Boot, Jan Oosting, Jaap D.H. van Eendenburg, Peter J.K. Kuppen, Hans Morreau, Tom van Wezel;
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:e0184900.1-e0184900.16(2017)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-813

Cell line databases/resources

cancercelllines; CVCL_EG22
DepMap; ACH-002659
DSMZCellDive; ACC-813

Encyclopedic resources

Wikidata; Q54899178

Gene expression databases

GEO; GSM1655604
GEO; GSM1655627

Entry history

Entry creation

13-Jul-2016

Last entry update

10-Apr-2025

Version number