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Cellosaurus JVE015 (CVCL_EG16)

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Cell line name JVE015
Synonyms JVE-015
Accession CVCL_EG16
Resource Identification Initiative To cite this cell line use: JVE015 (RRID:CVCL_EG16)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: ~3-4 days (DSMZ=ACC-786).
Microsatellite instability: Stable (MSS) (PubMed=26894854).
Omics: Genomics; DNA methylation analysis.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Colon, sigmoid; UBERON=UBERON_0001159.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1114Ter (c.3340C>T); ClinVar=VCV000236589; Zygosity=Heterozygous (PubMed=26894854; DepMap=ACH-002654).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Unspecified (PubMed=26894854; DepMap=ACH-002654).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Homozygous (DepMap=ACH-002654).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-786; PubMed=26894854

Markers:
AmelogeninX
CSF1PO12
D2S133818,19
D3S135816
D5S81811,12
D7S8209,11
D8S117913
D13S31711,12
D16S5399
D18S5115
D19S43313,14
D21S1130 (PubMed=26894854)
30,32.2 (DSMZ=ACC-786)
FGA23
Penta D11
Penta E11,12
TH016,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=26894854; DOI=10.18632/oncotarget.7391; PMCID=PMC4924731
Arnoud Boot, Jaap D.H. van Eendenburg, Stijn Crobach, Dina Ruano, Frank Speetjens, Jan Calame, Jan Oosting, Hans Morreau, Tom van Wezel;
Characterization of novel low passage primary and metastatic colorectal cancer cell lines.
Oncotarget 7:14499-14509(2016)

PubMed=28931069; DOI=10.1371/journal.pone.0184900; PMCID=PMC5607170
Arnoud Boot, Jan Oosting, Jaap D.H. van Eendenburg, Peter J.K. Kuppen, Hans Morreau, Tom van Wezel;
Methylation associated transcriptional repression of ELOVL5 in novel colorectal cancer cell lines.
PLoS ONE 12:e0184900.1-e0184900.16(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-786
Cell line databases/resources cancercelllines; CVCL_EG16
DepMap; ACH-002654
DSMZCellDive; ACC-786
Encyclopedic resources Wikidata; Q54899171
Gene expression databases GEO; GSM1655597
GEO; GSM1655623
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number16