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Cellosaurus HPSI0614i-lepk_4 (CVCL_EF10)

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Cell line name HPSI0614i-lepk_4
Synonyms WTSIi263-B; WTSIi329-A
Accession CVCL_EF10
Resource Identification Initiative To cite this cell line use: HPSI0614i-lepk_4 (RRID:CVCL_EF10)
Comments From: Cambridge BioResource; Cambridge; United Kingdom.
From: Wellcome Trust Sanger Institute; Hinxton; United Kingdom.
Population: Caucasian; British.
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Genomics; Whole genome sequencing.
Omics: Proteomics.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_EF09 ! HPSI0614i-lepk_1
Sex of cell Female
Age at sampling 60-64Y
Category Induced pluripotent stem cell
Publications

PubMed=28489815; DOI=10.1038/nature22403; PMCID=PMC5524171
Helena Kilpinen, Angela Goncalves, Andreas Leha, Vackar Afzal, Kaur Alasoo, Sofie Ashford, Sendu Bala, Dalila Bensaddek, Francesco Paolo Casale, Oliver J. Culley, Petr Danecek ...Show all 43 authors... , Adam Faulconbridge, Peter W. Harrison, Annie Kathuria, Davis McCarthy, Shane A. McCarthy, Ruta Meleckyte, Yasin Memari, Nathalie Moens, Filipa Soares, Alice Mann, Ian Streeter, Chukwuma A. Agu, Alex Alderton, Rachel Nelson, Sarah Harper, Minal J. Patel, Alistair White, Sharad R. Patel, Laura Clarke, Reena Halai, Christopher Michael Kirton, Anja Kolb-Kokocinski, Philip Beales, Ewan Birney, Davide Danovi, Angus Iain Lamond, Willem Hendrik Ouwehand, Ludovic Vallier, Fiona Mary Watt, Richard Durbin, Oliver Stegle, Daniel J. Gaffney; Show fewer authors
Common genetic variation drives molecular heterogeneity in human iPSCs.
Nature 546:370-375(2017)

Cross-references
Cell line collections (Providers) ECACC; 77650414
Cell line databases/resources HipSci; HPSI0614i-lepk_4
hPSCreg; WTSIi263-B
Biological sample resources BioSamples; SAMEA3964256
Encyclopedic resources Wikidata; Q54891139
Gene expression databases ArrayExpress; E-MTAB-4057
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number14