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Cellosaurus PC3-PIP (CVCL_E9XK)

[Text version]
Cell line name PC3-PIP
Synonyms PC3/PIP; PC3-PSMA+
Accession CVCL_E9XK
Resource Identification Initiative To cite this cell line use: PC3-PIP (RRID:CVCL_E9XK)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3788; FOLH1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=10397265
Sam S. Chang, Victor E. Reuter, Warren D.W. Heston, Neil Harrison Bander, Lana S. Grauer, Paul B. Gaudin;
Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature.
Cancer Res. 59:3192-3198(1999)

PubMed=10933046; DOI=10.1038/sj.neo.7900018; PMCID=PMC1508130
Michael Chi Gong, Jean-Baptiste Latouche, Anja Krause, Warren D.W. Heston, Neil Harrison Bander, Michel Sadelain;
Cancer patient T cells genetically targeted to prostate-specific membrane antigen specifically lyse prostate cancer cells and release cytokines in response to prostate-specific membrane antigen.
Neoplasia 1:123-127(1999)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1