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Cellosaurus A549 BLTP3A-V5 clone C5 (CVCL_E9W4)

[Text version]
Cell line name A549 BLTP3A-V5 clone C5
Accession CVCL_E9W4
Resource Identification Initiative To cite this cell line use: A549 BLTP3A-V5 clone C5 (RRID:CVCL_E9W4)
Comments Population: Caucasian.
Characteristics: Using CRISPR/Cas9 a V5 tag was introduced just after p.Val904 of both alleles of BLTP3A (DOI=10.1101/2024.09.28.615015).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

DOI=10.1101/2024.09.28.615015
Michael George Hanna 4th, Hely Octavio Rodriguez-Cruz, Kenshiro Fujise, Yu-Mei Wu, C. Shan Xu, Song Pang, Zhuon-Ging Li, Mara Monetti, Pietro De Camilli;
BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM.
bioRxiv 2024:09.28.615015-09.28.615015(2024)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1