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Cellosaurus HES-3 MIXL1GFP/w (CVCL_E9D2)

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Cell line name HES-3 MIXL1GFP/w
Synonyms HES3 MIXL1GFP/+; HES3(MIXL1GFP/w); HES3/MIXL1 GFP; HES3 MIXL1-GFP; MIXL1-GFP HES3
Accession CVCL_E9D2
Resource Identification Initiative To cite this cell line use: HES-3 MIXL1GFP/w (RRID:CVCL_E9D2)
Comments Registration: Swiss research registry; BAG-hES-IMP-0076.
Characteristics: Using homologous recombination an EGFP reporter gene was introduced in one allele of the MIXL1 locus (PubMed=18032708).
Genetic integration: Method=Homologous recombination; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7158 (HES-3)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=18032708; DOI=10.1182/blood-2007-06-093609
Richard Paul Davis, Elizabeth S. Ng, Magdaline Sakkas, Anna Katherine Mossman, Koula Sourris, Andrew George Elefanty, Edouard G. Stanley;
Targeting a GFP reporter gene to the MIXL1 locus of human embryonic stem cells identifies human primitive streak-like cells and enables isolation of primitive hematopoietic precursors.
Blood 111:1876-1884(2008)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1