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Cellosaurus TK [Human brain lymphoma] (CVCL_E941)

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Cell line name TK [Human brain lymphoma]
Synonyms Tk
Accession CVCL_E941
Resource Identification Initiative To cite this cell line use: TK [Human brain lymphoma] (RRID:CVCL_E941)
Comments Population: Japanese.
Doubling time: 34 hours (PubMed=7059907).
Anecdotal: Cell line name corresponds to the initials of the patient from which it was established.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Central nervous system lymphoma (NCIt: C9301)
Primary central nervous system lymphoma (ORDO: Orphanet_46135)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B3QM (MTX-TK)
Sex of cell Male
Age at sampling 22Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1206

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,10
D7S82010,11
D13S3178,13
D16S5399,10
TH016
TPOX8,11
vWA17,19

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Publications

PubMed=6450513; DOI=10.18926/AMO/30542
Kanji Miyamoto, Keiko Miyano, Kazuo Tabuchi, Akira Nishimoto, Haruhiko Yoshida, Tokichi Yumoto, Toshio Tanaka;
Chromosome analysis of a brain malignant lymphoma cell line.
Acta Med. Okayama 34:117-122(1980)

PubMed=7059907; DOI=10.1002/1097-0142(19820201)49:3<456::AID-CNCR2820490311>3.0.CO;2-K
Isao Miyoshi, Ichiro Kubonishi, Shizuo Yoshimoto, Takao Hikita, Hiroshi Dabasaki, Toshio Tanaka, Ikuro Kimura, Kazuo Tabuchi, Akira Nishimoto;
Characteristics of a brain lymphoma cell line derived from primary intracranial lymphoma.
Cancer 49:456-459(1982)

PubMed=30993483; DOI=10.1007/s10147-019-01451-9
Azusa Hayano, Yasuo Takashima, Ryuya Yamanaka;
Cell-type-specific sensitivity of bortezomib in the methotrexate-resistant primary central nervous system lymphoma cells.
Int. J. Clin. Oncol. 24:1020-1029(2019)

PubMed=31510952; DOI=10.1186/s12885-019-6129-8; PMCID=PMC6739943
Yasuo Takashima, Takeshi Yoshimura, Yuichiro Kano, Azusa Hayano, Hiroaki Hondoh, Kazuhiro Ikenaka, Ryuya Yamanaka;
Differential expression of N-linked oligosaccharides in methotrexate-resistant primary central nervous system lymphoma cells.
BMC Cancer 19:910.1-910.11(2019)

Cross-references
Cell line collections (Providers) JCRB; JCRB1206
JCRB; NIHS0524 - Discontinued
Biological sample resources BioSample; SAMN03472435
Encyclopedic resources Wikidata; Q54972514
Entry history
Entry creation22-Oct-2012
Last entry update27-Nov-2025
Version number17