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Cellosaurus SW1990/Luciferase-2A-GFP (CVCL_E8T3)

[Text version]
Cell line name SW1990/Luciferase-2A-GFP
Synonyms SW1990 / Luciferase & GFP
Accession CVCL_E8T3
Resource Identification Initiative To cite this cell line use: SW1990/Luciferase-2A-GFP (RRID:CVCL_E8T3)
Comments Population: Caucasian.
Characteristics: Transduced by lentivirus with a EF1a-Luc-2A-eGFP-Rsv-PuroR construct (GenTarget=SC074-LG).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
Cell type: Epithelial cell of pancreas; CL=CL_0000083.
Sequence variations
  • Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1723 (SW1990)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Web pages Provider; GenTarget; SC074-LG; https://www.gentarget.com/product/human-sw1990-luciferase-gfp-stable-cells/
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1