Cellosaurus cell line SW1990/GFP (Puro) (CVCL

Entry history
Cell line name	SW1990/GFP (Puro)
Synonyms	SW1990 / GFP (Puro)
Accession	CVCL_E8T1
Resource Identification Initiative	To cite this cell line use: SW1990/GFP (Puro) (RRID:CVCL_E8T1)
Comments	Population: Caucasian. Characteristics: Transduced by lentivirus with a EF1a-eGFP-Rsv-PuroR construct (GenTarget=SC074-GP). Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106. Cell type: Epithelial cell of pancreas; CL=CL_0000083.
Sequence variations	Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease	Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1723 (SW1990)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Web pages	Provider; GenTarget; SC074-GP; https://www.gentarget.com/product/human-sw1990-gfp-puro-stable-cells/
Entry creation	14-Aug-2025
Last entry update	14-Aug-2025
Version number	1