Cellosaurus logo
expasy logo

Cellosaurus SHP-77/RFP (CVCL_E8SV)

[Text version]
Cell line name SHP-77/RFP
Synonyms SHP-77 / RFP
Accession CVCL_E8SV
Resource Identification Initiative To cite this cell line use: SHP-77/RFP (RRID:CVCL_E8SV)
Comments Population: Caucasian.
Characteristics: Transduced by lentivirus with a EF1a-RFP-Rsv-PuroR construct (GenTarget=SC085-R).
Genetic integration: Method=Transduction; Gene=FPbase; EGE3L; DsRed (Note=drFP583, red fluorescent protein from Discosoma sp.).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung, left upper lobe; UBERON=UBERON_0008952.
Sequence variations
  • Mutation; HGNC; HGNC:76; ABL1; Simple; p.Val1128Glu (c.3383T>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9801; RAC1; Simple; p.Tyr32Cys (c.95A>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Trp (c.528C>G); ClinVar=VCV000376572; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1693 (SHP-77)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Web pages Provider; GenTarget; SC085-R; https://www.gentarget.com/product/human-shp-77-rfp-stable-cells/
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1