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Cellosaurus SHP-77/Luciferase-2A-GFP (CVCL_E8ST)

[Text version]
Cell line name SHP-77/Luciferase-2A-GFP
Synonyms SHP-77 / Luciferase & GFP
Accession CVCL_E8ST
Resource Identification Initiative To cite this cell line use: SHP-77/Luciferase-2A-GFP (RRID:CVCL_E8ST)
Comments Population: Caucasian.
Characteristics: Transduced by lentivirus with a EF1a-Luc-2A-GFP-Rsv-PuroR construct (GenTarget=SC085-LG).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Lung, left upper lobe; UBERON=UBERON_0008952.
Sequence variations
  • Mutation; HGNC; HGNC:76; ABL1; Simple; p.Val1128Glu (c.3383T>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9801; RAC1; Simple; p.Tyr32Cys (c.95A>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Trp (c.528C>G); ClinVar=VCV000376572; Zygosity=Homozygous (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1693 (SHP-77)
Sex of cell Male
Age at sampling 54Y
Category Cancer cell line
Web pages Provider; GenTarget; SC085-LG; https://www.gentarget.com/product/human-shp-77-luciferase-gfp-stable-cells/
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1