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Cellosaurus T47D-PalR (CVCL_E8SG)

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Cell line name T47D-PalR
Accession CVCL_E8SG
Resource Identification Initiative To cite this cell line use: T47D-PalR (RRID:CVCL_E8SG)
Comments Population: Caucasian.
Doubling time: ~30 hours (KYinno=KC-1404).
Selected for resistance to: ChEBI; CHEBI_85993; Palbociclib (Ibrance).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) KYinno; KC-1404
Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1