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Cellosaurus WM9 RL (CVCL_E8FY)

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Cell line name WM9 RL
Accession CVCL_E8FY
Resource Identification Initiative To cite this cell line use: WM9 RL (RRID:CVCL_E8FY)
Comments Selected for resistance to: ChEBI; CHEBI_63637; Vemurafenib (Zelboraf; PLX4032).
Derived from site: Metastatic; Left axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6806 (WM9)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=31877948; DOI=10.3390/ijms21010113; PMCID=PMC6981576
Ewelina Dratkiewicz, Aleksandra Simiczyjew, Katarzyna Pietraszek-Gremplewicz, Justyna Wadzynska, Dorota Nowak;
Characterization of melanoma cell lines resistant to vemurafenib and evaluation of their responsiveness to EGFR- and MET-inhibitor treatment.
Int. J. Mol. Sci. 21:113.1-113.20(2019)

Entry history
Entry creation14-Aug-2025
Last entry update14-Aug-2025
Version number1