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Cellosaurus HEK-Blue TGF-beta v2 (CVCL_E8EK)

[Text version]
Cell line name HEK-Blue TGF-beta v2
Accession CVCL_E8EK
Resource Identification Initiative To cite this cell line use: HEK-Blue TGF-beta v2 (RRID:CVCL_E8EK)
Comments Characteristics: Designed to detect bioactive human and mouse TGF-beta by monitoring the activation of the TGF-beta/SMAD pathway (InvivoGen=hkb-tgfbv2).
Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a beta-globin minimal promoter fused to 3 SMAD3/4-binding elements (SBE) (InvivoGen=hkb-tgfbv2).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Cross-references
Cell line collections (Providers) InvivoGen; hkb-tgfbv2
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1