Cellosaurus HEK-Blue IL-31 (CVCL_E8EG)
| Cell line name | HEK-Blue IL-31 |
|---|---|
| Accession | CVCL_E8EG |
| Resource Identification Initiative | To cite this cell line use: HEK-Blue IL-31 (RRID:CVCL_E8EG) |
| Comments | Characteristics: Designed to detect bioactive human IL31 (but not mouse IL31) by monitoring the activation of the JAK/STAT5 pathway (InvivoGen=hkb-il31). Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of a STAT5-responsive promoter (InvivoGen=hkb-il31). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:18969; IL31RA. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:8507; OSMR. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11367; STAT5B. Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | InvivoGen; hkb-il31 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |