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Cellosaurus I3L6 (CVCL_E8E7)

[Text version]
Cell line name I3L6
Accession CVCL_E8E7
Resource Identification Initiative To cite this cell line use: I3L6 (RRID:CVCL_E8E7)
Comments Characteristics: Expression of Il4 is constitutive and under the control of a promoter/enhancer from an IgH (PubMed=2785856).
Genetic integration: Method=Transfection; Gene=MGI; MGI:96556; Il4.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Cell type: B-cell; CL=CL_0000236.
Disease Mouse multiple myeloma (NCIt: C125417)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_3949 (J558L)
Category Cancer cell line
Publications

PubMed=2785856; DOI=10.1016/0092-8674(89)90925-2
Tepper R.I., Pattengale P.K., Leder P.
Murine interleukin-4 displays potent anti-tumor activity in vivo.
Cell 57:503-512(1989)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1