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Cellosaurus BPS Bioscience MCF-7 TACSTD2 KO (CVCL_E8DL)

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Cell line name BPS Bioscience MCF-7 TACSTD2 KO
Synonyms TROP2 knockout MCF7
Accession CVCL_E8DL
Resource Identification Initiative To cite this cell line use: BPS Bioscience MCF-7 TACSTD2 KO (RRID:CVCL_E8DL)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:11530; TACSTD2.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Web pages Provider; BPS Bioscience; 82657; https://bpsbioscience.com/trop2-knockout-mcf7-cell-line-82657
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1