Cellosaurus HEK-Blue IFN-alpha/beta v2 (CVCL_E8DB)
| Cell line name | HEK-Blue IFN-alpha/beta v2 |
|---|---|
| Synonyms | HEK-Blue IFN-a/b v2 |
| Accession | CVCL_E8DB |
| Resource Identification Initiative | To cite this cell line use: HEK-Blue IFN-alpha/beta v2 (RRID:CVCL_E8DB) |
| Comments | Characteristics: Designed to detect bioactive human type I IFNs by monitoring the activation of the ISGF3 pathway. Has an improved Type I IFN response compared to HEK-Blue IFN-alpha/beta (Cellosaurus=CVCL_KT26) (InvivoGen=hkb-ifnabv2). Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of the ISG54 promoter (InvivoGen=hkb-ifnabv2). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:439; ALPP. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6131; IRF9. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11363; STAT2. Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr. Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0045 (HEK293) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Cross-references | |
| Cell line collections (Providers) | InvivoGen; hkb-ifnabv2 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |