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Cellosaurus MAC-T spCas9 #1 (CVCL_E8BZ)

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Cell line name MAC-T spCas9 #1
Accession CVCL_E8BZ
Resource Identification Initiative To cite this cell line use: MAC-T spCas9 #1 (RRID:CVCL_E8BZ)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9 (Note=Codon optimized).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Mammary alveolar epithelial cell; CL=CL_0002325.
Species of origin Bos taurus (Bovine) (NCBI Taxonomy: 9913)
Breed/subspecies: Holstein; VBO=VBO_0000237.
Hierarchy Parent: CVCL_U226 (MAC-T)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=36930414; DOI=10.1007/s11626-023-00756-4
Alexander J. Trevarton, Emily Rose Mears, Janelle Moody, Thomas John Lopdell, Thaize Quiroga Chometon, John A. Taylor, Carol J.H. Wang, Mathew Douglas Littlejohn, Russell G. Snell;
Development of SpCas9-expressing bovine mammary epithelial cell lines.
In Vitro Cell. Dev. Biol. Anim. 59:163-165(2023)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2