Cellosaurus logo
expasy logo

Cellosaurus ff-2 (CVCL_E8B7)

[Text version]
Cell line name ff-2
Accession CVCL_E8B7
Resource Identification Initiative To cite this cell line use: ff-2 (RRID:CVCL_E8B7)
Comments Group: Amphibian cell line.
Characteristics: Expresses MHC class I but not MHC class II molecules (DOI=10.1016/B978-012442710-5.50265-3; PubMed=9914916).
Characteristics: Tumorigenic in larval but not adult syngeneic hosts (DOI=10.1016/B978-012442710-5.50265-3; PubMed=9914916).
Characteristics: Displays a dual B-cell and T-cell phenotype (PubMed=9914916).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Disease Xenopus thymic lymphoma (NCIt: C215148)
Species of origin Xenopus laevis (African clawed frog) (NCBI Taxonomy: 8355)
Breed/subspecies: ff.
Hierarchy Children:
CVCL_E8BA (ff-2.64)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages Provider; URMC; -; https://www.urmc.rochester.edu/microbiology-immunology/research/xenopus-laevis/models/cell-lines
Publications

PubMed=7620321; DOI=10.1155/1994/37392; PMCID=PMC2275934
Robert J., Guiet C., Du Pasquier L.
Lymphoid tumors of Xenopus laevis with different capacities for growth in larvae and adults.
Dev. Immunol. 3:297-307(1994)

DOI=10.1016/B978-012442710-5.50265-3
Robert J., Du Pasquier L.
Xenopus lymphoid tumor cell lines.
(In book chapter) Immunology methods manual. The comprehensive sourcebook of techniques, Vol. 2; Lefkovits I. (eds.); pp.2367-2377; Academic Press; New York; USA (1996)

PubMed=9914916; DOI=10.1111/j.1600-065x.1998.tb01266.x
Robert J., Cohen N.
Evolution of immune surveillance and tumor immunity: studies in Xenopus.
Immunol. Rev. 166:231-243(1998)

PubMed=19273061; DOI=10.2741/3238; PMCID=PMC2749489
Goyos A., Robert J.
Tumorigenesis and anti-tumor immune responses in Xenopus.
Front. Biosci. 14:167-176(2009)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1