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Cellosaurus HeLa-P4 (CVCL_E8AR)

[Text version]
Cell line name HeLa-P4
Synonyms HeLa P4; P4; HeLa-LTR-lacZ clone Z24 CD4 clone P4
Accession CVCL_E8AR
Resource Identification Initiative To cite this cell line use: HeLa-P4 (RRID:CVCL_E8AR)
Comments Population: African American.
Characteristics: Expression of CD4 is under the control of a mouse PGK promoter (PubMed=7520946).
Characteristics: Transfected with a construct pMA175 containing the HIV-1 BRU LTR that allows expression of lacZ when Tat is present (from parent cell line).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1678; CD4.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E8AP (HeLa-LTR-lacZ clone Z24)
Children:
CVCL_1H21 (HeLa-P4-R5 MAGI)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=7520946; DOI=10.1006/jmbi.1994.1542
Charneau P., Mirambeau G., Roux P., Paulous S., Buc H., Clavel F.
HIV-1 reverse transcription. A termination step at the center of the genome.
J. Mol. Biol. 241:651-662(1994)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1