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Cellosaurus WeWak1 (CVCL_E871)

[Text version]
Cell line name WeWak1
Synonyms Wewak1; WEWAK1; Wewak-1
Accession CVCL_E871
Resource Identification Initiative To cite this cell line use: WeWak1 (RRID:CVCL_E871)
Comments Part of: 12th International Histocompatibility Workshop (12IHW) cell line panel.
Population: Papuan.
Virology: Contains a complete EBV genome (strain WeWak1) which has been sequenced (PubMed=25787276).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Caution: Could be identical to QIMR-WW1-LCL (Cellosaurus=CVCL_W930).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7553; MYC; Simple; p.Pro72Thr (c.214C>A); Zygosity=Unspecified (PubMed=8108117).
HLA typing Source: IPD-IMGT/HLA=11558
Class I
HLA-AA*11:01,24:02
HLA-BB*27:04:01,15:06
HLA-CC*04:01,12:02
Class II
HLA-DPDPB1*01:01:01,03:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=8108117
Thomas Albert, Birgit Urlbauer, Franz Kohlhuber, Bettina Hammersen, Dirk Eick;
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9583678; DOI=10.1038/sj.onc.1201704
Matthew Brimmell, Rezzeline Mendiola, Jonathan Mangion, Graham Packham;
BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability.
Oncogene 16:1803-1812(1998)

PubMed=25787276; DOI=10.1128/JVI.03614-14; PMCID=PMC4442510
Anne L. Palser, Nicholas Edwin Grayson, Robert E. White, Craig Corton, Samantha Correia, Mohammed M. Ba Abdullah, Simon J. Watson, Matthew Cotten, John R. Arrand, Paul G. Murray, Martin John Allday, Alan Bernard Rickinson, Lawrence S. Young ...Show all 15 authors... , Paul J. Farrell, Paul Kellam; Show fewer authors
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.
J. Virol. 89:5222-5237(2015)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001; PMCID=PMC6599558
Lisa E. Creary, Sandra G. Guerra, Winnie Chong, Colin J. Brown, Thomas R. Turner, James Robinson, Will P. Bultitude, Neema P. Mayor, Steven G.E. Marsh, Katsuyuki Saito, Kevin Lam, Jamie L. Duke, Timothy L. Mosbruger ...Show all 41 authors... , Deborah Ferriola, Dimitrios S. Monos, Amanda Willis, Medhat Askar, Gottfried F. Fischer, Chee Loong Saw, Jiannis Ragoussis, Martin Petrek, Carles Serra-Pages, Manel Juan Otero, Catherine Stavropoulos-Giokas, Amalia Dinou, Reem Ameen, Salem Al Shemmari, Eric Spierings, Ketevan Gendzekhadze, Gerald P. Morris, Qiu-Heng Zhang, Zahra Kashi, Susan Hsu, Sridevi Gangavarapu, Kalyan C. Mallempati, Fumiko Yamamoto, Kazutoyo Osoegawa, Tamara Vayntrub, Chia-Jung Chang, John A. Hansen, Marcelo A. Fernandez-Vina; Show fewer authors
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) ECACC; 94022553
Cell line databases/resources dbMHC; 49061
IHW; IHW09219
IPD-IMGT/HLA; 11558
Encyclopedic resources Wikidata; Q54993790
Polymorphism and mutation databases Cosmic; 2804851
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19