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Cellosaurus HEK-293 rCTR C1b clone G12-E12 (CVCL_E7XF)

[Text version]
Cell line name HEK-293 rCTR C1b clone G12-E12
Synonyms G12-E12
Accession CVCL_E7XF
Resource Identification Initiative To cite this cell line use: HEK-293 rCTR C1b clone G12-E12 (RRID:CVCL_E7XF)
Comments Characteristics: Expresses ~60,000 receptors/cell (PubMed=7723741).
Genetic integration: Method=Transfection; Gene=RGD; 621001; Calcr (Note=Isoform C1b).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=7723741; DOI=10.1016/S0026-895X(25)08628-6
Houssami S., Findlay D.M., Brady C.L., Martin T.J., Epand R.M., Moore E.E., Murayama E., Tamura T., Orlowski R.C., Sexton P.M.
Divergent structural requirements exist for calcitonin receptor binding specificity and adenylate cyclase activation.
Mol. Pharmacol. 47:798-809(1995)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1