Cellosaurus cell line HEK-293 rbCTR C1a (CVCL

Entry history
Cell line name	HEK-293 rbCTR C1a
Synonyms	C1a-HEK
Accession	CVCL_E7X9
Resource Identification Initiative	To cite this cell line use: HEK-293 rbCTR C1a (RRID:CVCL_E7X9)
Comments	Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P79222; Rabbit CALCR (Note=Isoform C1a with a HA-tag). Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0045 (HEK293)
Sex of cell	Female
Age at sampling	Fetus
Category	Transformed cell line
Publications	PubMed=8940110; DOI=10.1074/jbc.271.49.31127 Jia-Fwu Shyu, Daisuke Inoue, Roland E. Baron, William C. Horne; The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C. J. Biol. Chem. 271:31127-31134(1996) PubMed=9677414; DOI=10.1074/jbc.273.31.19809 Yan Chen, Jia-Fwu Shyu, Anu Santhanagopal, Daisuke Inoue, Jean-Pierre David, S. Jeffrey Dixon, William C. Horne, Roland E. Baron; The calcitonin receptor stimulates Shc tyrosine phosphorylation and Erk1/2 activation. Involvement of Gi, protein kinase C, and calcium. J. Biol. Chem. 273:19809-19816(1998)
Entry creation	10-Apr-2025
Last entry update	14-Aug-2025
Version number	2