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Cellosaurus HEK-293 rbCTR C1a (CVCL_E7X9)

[Text version]
Cell line name HEK-293 rbCTR C1a
Synonyms C1a-HEK
Accession CVCL_E7X9
Resource Identification Initiative To cite this cell line use: HEK-293 rbCTR C1a (RRID:CVCL_E7X9)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P79222; Rabbit CALCR (Note=Isoform C1a with a HA-tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=8940110; DOI=10.1074/jbc.271.49.31127
Shyu J.-F., Inoue D., Baron R.E., Horne W.C.
The deletion of 14 amino acids in the seventh transmembrane domain of a naturally occurring calcitonin receptor isoform alters ligand binding and selectively abolishes coupling to phospholipase C.
J. Biol. Chem. 271:31127-31134(1996)

PubMed=9677414; DOI=10.1074/jbc.273.31.19809
Chen Y., Shyu J.-F., Santhanagopal A., Inoue D., David J.-P., Dixon S.J., Horne W.C., Baron R.E.
The calcitonin receptor stimulates Shc tyrosine phosphorylation and Erk1/2 activation. Involvement of Gi, protein kinase C, and calcium.
J. Biol. Chem. 273:19809-19816(1998)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1