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Cellosaurus HEK293-Flag-beta2AR-TYY (CVCL_E7X4)

[Text version]
Cell line name HEK293-Flag-beta2AR-TYY
Accession CVCL_E7X4
Resource Identification Initiative To cite this cell line use: HEK293-Flag-beta2AR-TYY (RRID:CVCL_E7X4)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:286; ADRB2 (Note=With p.Thr68Phe, Tyr132Gly, p.Tyr219Ala and a N-terminal FLAG tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=16280323; DOI=10.1074/jbc.M506576200
Sudha Kaup Shenoy, Matthew T. Drake, Christopher D. Nelson, Daniel A. Houtz, Kun-Hong Xiao, Srinivasan Madabushi, Eric Reiter, Richard T. Premont, Olivier Lichtarge, Robert Joseph Lefkowitz;
Beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
J. Biol. Chem. 281:1261-1273(2006)

Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2