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Cellosaurus NCI-H460(Cas9) (CVCL_E7JD)

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Cell line name NCI-H460(Cas9)
Accession CVCL_E7JD
Resource Identification Initiative To cite this cell line use: NCI-H460(Cas9) (RRID:CVCL_E7JD)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000045117; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung large cell carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0459 (NCI-H460)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Web pages Provider; BRICS; ECC3003; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3937
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1